Product Details:
Minimum Order Quantity | 1 Vial |
Strength | 1000 mg |
Pack Size | 10 ml |
Pack Type | Vial |
Injection Site | IV |
Form | Powder |
Composition | Ceftizoxime Injection IP |
Brand | Zetocet |
Manufactured By | ShinePro |
Shelf Life | 36 Months |
etocet Ceftizoxime Injection IP, 1 gm, 1000 mg
Zetocet Ceftizoxime Injection is a sterile, parenteral antibiotic formulation containing 1 gram of ceftizoxime sodium per vial. Ceftizoxime is a third-generation cephalosporin antibiotic with a broad spectrum of activity against both Gram-positive and Gram-negative bacteria. It is commonly used in the treatment of a wide range of bacterial infections, particularly in situations where the causative organism is resistant to other antibiotics.
Pharmacology and Mechanism of Action: Ceftizoxime works by inhibiting bacterial cell wall synthesis. It binds to specific penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. This binding disrupts the transpeptidation process, which is essential for cell wall construction, leading to cell lysis and death of the bacteria. The antibiotic demonstrates strong activity against many aerobic and anaerobic Gram-negative bacteria, including strains resistant to penicillins and some cephalosporins.
Indications: Zetocet Ceftizoxime Injection is indicated for the treatment of various bacterial infections caused by susceptible organisms. It is commonly used in the management of:
Dosage and Administration: The dosage of Zetocet Ceftizoxime Injection varies depending on the type and severity of the infection, as well as the patient's age and renal function. Typically, the dosage ranges from 1 to 2 grams administered every 8 to 12 hours. For severe infections, higher doses may be used. The injection should be administered intravenously (IV) or intramuscularly (IM) by a healthcare professional. The solution should be prepared immediately before administration and administered under sterile conditions.
Contraindications and Precautions: Zetocet Ceftizoxime Injection is contraindicated in patients with a known hypersensitivity to cephalosporins or any component of the formulation. Caution should be exercised in patients with a history of hypersensitivity reactions to penicillins or other beta-lactam antibiotics, as cross-reactivity may occur. It should also be used with caution in individuals with renal impairment, as dose adjustments may be necessary.
Side Effects: Common side effects of Zetocet Ceftizoxime Injection include gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Local reactions at the injection site, such as pain and swelling, may also occur. Allergic reactions, ranging from rash and itching to more severe reactions like anaphylaxis, may occur but are less common. Prolonged use may lead to superinfection with non-susceptible organisms, including fungi.
Drug Interactions: Ceftizoxime may interact with other drugs, including anticoagulants, which may require monitoring of coagulation parameters. The use of ceftizoxime in combination with other nephrotoxic agents may increase the risk of renal toxicity. It is important to review all current medications and consult a healthcare provider to manage potential interactions.
Storage: Zetocet Ceftizoxime Injection should be stored at room temperature, away from light and moisture. The solution should be prepared and used according to the manufacturer’s guidelines to ensure its efficacy and safety.
Additional Information: